Cochrane meta-analysis: Single versus double layer anastomosis
Summary:
- Seven randomised controlled trials of 842 patients undergoing single-layer gastrointestinal anastomosis versus double layer gastrointestinal anastomosis were included
- 408 patients underwent single-layer gastrointestinal anastomosis group and 432 patients underwent double layer gastrointestinal anastomosis group.
- The incidence of anastomotic dehiscence, peri-operative complications and mortality was no different between the two groups.
- Average hospital stay following single-layer gastrointestinal anastomosis and double layer gastrointestinal anastomosis was also comparable.
- However, single-layer gastrointestinal anastomosis was superior in terms of shorter operative time.
Key finding: Single-layer gastrointestinal anastomosis may routinely be used for gastrointestinal anastomosis following bowel resection.
No difference was detected between double-layer intestinal anastomosis and single-layer gastrointestinal anastomosis in terms of anastomotic leaks or any other measured outcome.
Considering the additional time taken to perform a double-layer anastomosis and costs of additional suture material, single-layer intestinal anastomosis may be the optimal choice for most surgical situations.