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Cochrane meta-analysis: Single versus double layer anastomosis

Summary:

  • Seven randomised controlled trials of 842 patients undergoing single-layer gastrointestinal anastomosis versus double layer gastrointestinal anastomosis were included
  • 408 patients underwent single-layer gastrointestinal anastomosis group and 432 patients underwent double layer gastrointestinal anastomosis group.
  • The incidence of anastomotic dehiscence, peri-operative complications and mortality was no different between the two groups.
  • Average hospital stay following single-layer gastrointestinal anastomosis and double layer gastrointestinal anastomosis was also comparable.
  • However, single-layer gastrointestinal anastomosis was superior in terms of shorter operative time.

 

Key finding: Single-layer gastrointestinal anastomosis may routinely be used for gastrointestinal anastomosis following bowel resection.

 

 

No difference was detected between double-layer intestinal anastomosis and single-layer gastrointestinal anastomosis in terms of anastomotic leaks or any other measured outcome.

 

Considering the additional time taken to perform a double-layer anastomosis and costs of additional suture material, single-layer intestinal anastomosis may be the optimal choice for most surgical situations.

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